Objective 4

To elucidate pathways into multimorbidity

Objective 4: To elucidate interdependencies between physical and mental health and pathways into multimorbidity in changing family systems.

Objective 4 aims to capture and understand mutual feedback effects between physical and mental disease and longitudinal pathways of multimorbidity emergence in changing family systems.

Major goals of Objective 4 are to elucidate the biopsychosocial pathways underlying multimorbidity dynamics, especially related to short- and longer-term consequences of depression and cardiometabolic risk factors and disorders. The Objective will also investigate how pre-disorder pathways of risk and resilience are shaped by interactions between genetic susceptibility and the physical, social, and family environment.


Research Questions:

  • What are the social, biological, and biosocial pathways underlying the interrelatedness of mental and physical disease and multimorbidity
  • How do changing family systems contribute to and protect against adverse disease trajectories?

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